Fentanyl is in a class of medications called narcotic (opiate) analgesics. It works by changing the way the brain and nervous system respond to pain. A program has been set up for each fentanyl product to decrease the risk of using the medication.

That included just over 28,100 opioid product listings and over 13,500 opioid promotional and review forum traces. These were linked to over 5,100 opioid suppliers’ IDs and nearly 2,800 buyers’ IDs. Champagne-Langabeer is an assistant professor of health informatics at the University of Texas Health Science Center at Houston. Log in or create an account for a personalized experience based on your selected interests.
- Fentanyl and similar compounds like carfentanil are powerful synthetic opioids 50 to 100 times more potent than morphine.
- Coroners’ offices and state crime laboratories do not test for fentanyl unless given a specific reason to do so.
- You’ll find up-to-date fact sheets, webinars, manuals, training guides, and more.
- It is relatively easy to produce and is much more potent than heroin.
General Health
An individual’s tolerance to fentanyl will impact the amount required to cause a fatal overdose. Opioids include prescription painkillers (such as oxycodone) and illegal drugs (such as heroin and fentanyl). Producers of illicit fentanyl add it to or substitute it for other street drugs to increase profits and the potential for addiction — which keeps their customers coming back for more. Comparable to fentanyl, fentanyl analogs have similar chemical structure and effects. Common pharmaceutical industry fentanyl analogs used during surgery include sufentanil (Sufenta), alfentanil (Alfenta) and remifentanil (Ultiva).
Responding To An Overdose

In a time of noise, confusion, and spin, we’re committed to clarity, truth, and depth — even when it’s hard. The sellers preferred to ship purchases through the international arm of the U.S. They also preferred to get paid through cryptocurrency, Bitcoin in particular, but Western Union, PayPal, bank transfers, credit cards, and prepaid gift cards were also accepted. The subcommittee identified more than 500 sales, totaling $230,000, that involved the six online sellers.
Online Pharmacies
However, harm reduction proponents have told VICE World News the programs aren’t meeting demand. Portman and a bipartisan group of senators have actually introduced legislation to require the Postal Service to collect this electronic data. It is also an idea that President Trump has at times endorsed.
Fentanyl Dealers Are Bypassing Dark Web Restrictions To Sell Deadly Precursors Online: Here’s How
Selling or giving away this medication may cause severe harm or death to others and is against the law. “In order to buy the product, you have to use cryptocurrency, which requires a high level of technology,” she said. With the popularity of drug dealers mixing fentanyl into other drugs, fentanyl test strips can help people who use drugs identify whether what they are taking contains fentanyl or not. These small, paper strips can be obtained at needle-exchange sites, are easy to use and only take minutes to interpret. The use of fentanyl citrate injection with CYP3A4 inducers or stopping the CYP3A4 inhibitor will require close and repetitive monitoring of the patient.
Fentanyl can also be “diverted.” That’s when the drug is prescribed by a doctor but isn’t used as directed or is sold or given to someone else. Talk to your doctor about the risks of using this medication. Postings included product photos and reviews, as well as instructions for buying the items. Soon after a product had been posted and sold, the seller and site disappeared, according to the report recently published in the Journal of Medical Internet Research.
In An Emergency? Need Treatment?
Due to the risk of the drug being mixed with other substances, it is now essential to obtain test strips, which can tell a person if fentanyl is present in the tested substance. Fentanyl + alcohol may increase the risk of respiratory depression and possible overdose. Once you’ve been taking fentanyl for a while, your body gets used to it and stopping can be very hard. It can be hard to function without the drug in your system. Most people need help from a health professional or program to successfully quit.
Why Is This Medication Prescribed?

Be wary of websites that offer fentanyl without a prescription, as these are likely illegal and potentially dangerous. Either way, that might seem like a high cost for a small amount of drugs. However, fentanyl is chosen by illegal drug producers and drug dealers for its strength and affordability.
Call your pharmacist or the manufacturer if you have questions or need help disposing of unneeded medication. This medication should not be prescribed for other uses; ask your doctor or pharmacist for more information. Discarded fentanyl patches may still contain significant amounts of the drug. This can result in misuse if someone removes the gel contents from discarded patches. Research has found that pregnant women with untreated addiction may be less likely to get regular prenatal care.
- “But then, how many overdoses do you need to do before this is the program that you launch?
- The use of fentanyl citrate injection with CYP3A4 inducers or stopping the CYP3A4 inhibitor will require close and repetitive monitoring of the patient.
- The large number of overdose deaths involving fentanyl highlights the need to ensure people most at risk can access care, as well as the need to expand prevention and response activities.
- People can also unknowingly consume fentanyl when it is mixed into or sold as other drugs, including heroin, cocaine, or counterfeit pills.
- For those balancing recovery with daily responsibilities, outpatient services offer a flexible yet supportive approach.
- Regardless of how vendors try to conceal their fentanyl listings on the dark web, their activities can nevertheless be exposed through blockchain analytics.
What Should I Know About Storage And Disposal Of This Medication?
Fentanyl is a potent and dangerous drug, and the use of drugs without medical supervision carries significant risks. When used, fentanyl quickly binds to opioid receptors in the brain, producing intense feelings of euphoria and pain relief. This effect can lead to both physical and psychological dependence, even with short-term use. Adverse effects occur based on dose, timing, and monitoring. The dose in a medical setting aims to use the least amount of the drug to achieve the desired effect of pain control. However, illicit use is usually aimed at using a dose that will maximize euphoria, therefore increasing the dangers.
Overdose rates have skyrocketed for nonmedical use, whether in those addicted or from accidental deaths. If you or someone you know is showing these symptoms, it is important to seek professional help immediately. Users and family members should have immediate access to naloxone (Narcan), an opioid agonist medication that rapidly reverses opioid overdose. “Fentanyl is in the supply of many drugs on the street,” explains Dr. Donald. “It took time to create this opioid epidemic, and it is taking time as we learn how to best combat it. There is hope, and there is treatment that works, is safe and is effective.” When it is intentionally misused, fentanyl often shows up as a powder, spiked on blotter paper or is mixed with or substituted for heroin and other street drugs.
Treatment Options For Fentanyl Addiction
As a synthetic opioid, fentanyl attaches to the body’s opioid receptors, which are found in areas of the brain that control pain and emotions. When fentanyl binds to these receptors, it can create intense feelings of euphoria and relaxation, but it also carries a high risk for addiction and overdose. Fentanyl and similar compounds like carfentanil are powerful synthetic opioids 50 to 100 times more potent than morphine. Fentanyl is a synthetic opioid that can be prescribed by doctors for pain management (National Institute on Drug Abuse NIDA, 2021). It is also increasingly found mixed into street drugs (Drug Enforcement Administration DEA, 2024). Understanding the dangers of fentanyl is crucial, especially for individuals who might unknowingly consume it or use it without a doctor’s prescription.